PXD018590

PXD018590 is an original dataset announced via ProteomeXchange.

Title	Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression
Description	The molecular networks underlying Alzheimer’s disease (AD) are not well-defined. We present temporal profiling of >14,000 proteins and >34,000 phosphosites at the asymptomatic and symptomatic stages of AD, deep proteomics analysis of transgenic mouse models.
HostingRepository	PRIDE
AnnounceDate	2020-04-16
AnnouncementXML	Submission_2020-04-15_22:51:27.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuxin Li
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-04-15 15:54:38	ID requested
⏵ 1	2020-04-15 22:56:10	announced

Bai B, Wang X, Li Y, Chen PC, Yu K, Dey KK, Yarbro JM, Han X, Lutz BM, Rao S, Jiao Y, Sifford JM, Han J, Wang M, Tan H, Shaw TI, Cho JH, Zhou S, Wang H, Niu M, Mancieri A, Messler KA, Sun X, Wu Z, Pagala V, High AA, Bi W, Zhang H, Chi H, Haroutunian V, Zhang B, Beach TG, Yu G, Peng J, Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression. Neuron, 105(6):975-991.e7(2020) [pubmed]

submitter keyword: AD mouse model, brain, TMT-LC/LC-MS/MS

Junmin Peng
contact affiliation	St. Jude Children’s Research Hospital
contact email	Junmin.Peng@stjude.org
lab head
Yuxin Li
contact affiliation	St. Jude Children's Research Hospital
contact email	yuxin.li@stjude.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/04/PXD018590

PRIDE project URI

• PRIDE
  1. PXD018590
     1. Label: PRIDE project
     2. Name: Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression