PXD018416 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Global Proteomic Profiling in Chronic Iron-Exposed Fallopian Tube Secretory Epithelial Cells |
Description | We previously published (Oncogenesis, Rockfield et al., 2019) that chronic iron exposure (with ferric ammonium citrate, FAC) in immortalized fallopian tube secretory epithelial cells resulted in increased growth and migratory propensity. Our focused analyses identified a subset of oncogenic markers, including EVI1 (amplified at 3q26.2 in high grade serous epithelial ovarian tumors), that were altered following long term iron treatment. Herein, we have extended these studies to global proteomics analyses via a mass spectrometry (MS)-based approach. |
HostingRepository | PRIDE |
AnnounceDate | 2021-09-09 |
AnnouncementXML | Submission_2021-09-08_23:47:13.883.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Stanley Stevens |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-04-07 07:52:33 | ID requested | |
⏵ 1 | 2021-09-08 23:47:14 | announced | |
Publication List
Chhabra R, Rockfield S, Guergues J, Nadeau OW, Hill R, Stevens SM, Nanjundan M, Global miRNA/proteomic analyses identify miRNAs at 14q32 and 3p21, which contribute to features of chronic iron-exposed fallopian tube epithelial cells. Sci Rep, 11(1):6270(2021) [pubmed] |
Keyword List
submitter keyword: proteomic profiling, ferric ammonium citrate, fallopian tube secretory epithelial cells, ovarian cancer, initiation events |
Contact List
Meera Nanjundan |
contact affiliation | Department of Cell Biology, Microbiology, and Molecular Biology University of South Florida Tampa, FL, USA 33620 |
contact email | mnanjund@usf.edu |
lab head | |
Stanley Stevens |
contact affiliation | Albany College of Pharmacy and Health Sciences |
contact email | stanley.stevens@acphs.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD018416 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD018416
- Label: PRIDE project
- Name: Global Proteomic Profiling in Chronic Iron-Exposed Fallopian Tube Secretory Epithelial Cells