PXD018409

PXD018409 is an original dataset announced via ProteomeXchange.

Title	Triggering acute RyR1 Ca2+ leak leads to improved mitochondrial remodelling and function
Description	C2C12 myotubes at day 7 of differentiation were stimulated with a single session of SIT (6 x 30s with 4 min at rest) and were immediately after the stimulation treated or not with 10 uM S107 drug for 72h. The myotubes were then harvested at 72h post stimulation (for SIT condition) and 72h post stimulation and S107 treatment (for SIT S107 condition) for mass spectrometry analysis using the proteomics approach. N = 5 independent myotube wells per condition.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:51:01.588.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Manfredo Quadroni
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2020-04-06 22:34:43	ID requested
1	2021-10-20 05:16:06	announced
2	2021-12-08 02:48:48	announced	2021-12-08: Updated publication reference for DOI(s): 10.1038/s41467-021-27422-1.
3	2021-12-17 13:50:21	announced	2021-12-08: Updated publication reference for DOI(s): 10.1038/s41467-021-27422-1. 2021-12-17: Updated publication reference for PubMed record(s): 34893614. 2021-12-17: Updated publication reference for DOI(s): 10.1038/s41467-021-27422-1.
⏵ 4	2023-11-14 08:51:02	announced	2023-11-14: Updated project metadata.

Zanou N, Dridi H, Reiken S, Imamura de Lima T, Donnelly C, De Marchi U, Ferrini M, Vidal J, Sittenfeld L, Feige JN, Garcia-Roves PM, Lopez-Mejia IC, Marks AR, Auwerx J, Kayser B, Place N, leak enhances NADH-linked mitochondrial respiratory capacity. Nat Commun, 12(1):7219(2021) [pubmed]

submitter keyword: short interval training,muscle fibers, ryanodine receptor

Nicolas Place
contact affiliation	Institut des Sciences du Sport de l'Université de Lausanne Bâtiment Synathlon 1015 Lausanne Switzerland
contact email	nicolas.place@unil.ch
lab head
Manfredo Quadroni
contact affiliation	University of Lausanne
contact email	manfredo.quadroni@unil.ch
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/10/PXD018409

PRIDE project URI

• PRIDE
  1. PXD018409
     1. Label: PRIDE project
     2. Name: Triggering acute RyR1 Ca2+ leak leads to improved mitochondrial remodelling and function