PXD018363

PXD018363 is an original dataset announced via ProteomeXchange.

Title	Proteome-scale correlation analysis between urinary extracellular vesicle (uEV) and kidney
Description	We profiled the proteomes of uEV and kidney from twelve rats. Six of them were under a standard diet while the other six under a high potassium diet for 4 days. During the revision stage of this project, we further put five rats in metabolic cages for two days, fed with the high potassium diet for 2 days. We made proteome-scale correlation analyses of uEV and kidney using absolute label-free quantification algorithm iBAQ under these three conditions: control, high K 4day, and high K 2 day. We also did label-free quantification (LFQ) to investigate the protein abundance changes in uEV and kidney between control and high K 4day.
HostingRepository	PRIDE
AnnounceDate	2021-07-28
AnnouncementXML	Submission_2021-07-27_22:14:45.111.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qi Wu
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	carbamoylated residue; phosphorylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion; Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-04-04 09:17:42	ID requested
1	2021-07-27 09:07:09	announced
⏵ 2	2021-07-27 22:14:45	announced	2021-07-28: Updated project metadata.

10.1681/ASN.2020071035;

Wu Q, Poulsen SB, Murali SK, Grimm PR, Su XT, Delpire E, Welling PA, Ellison DH, Fenton RA, Large-Scale Proteomic Assessment of Urinary Extracellular Vesicles Highlights Their Reliability in Reflecting Protein Changes in the Kidney. J Am Soc Nephrol, 32(9):2195-2209(2021) [pubmed]

submitter keyword: urinary extracellular vesicle (uEV), kidney, correlation,proteome

Robert A. Fenton
contact affiliation	Department of Biomedicine, Aarhus University, Denmark
contact email	robert.a.fenton@biomed.au.dk
lab head
Qi Wu
contact affiliation	Department of Biomedicine, Aarhus University
contact email	qi.wu@biomed.au.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/07/PXD018363

PRIDE project URI

• PRIDE
  1. PXD018363
     1. Label: PRIDE project
     2. Name: Proteome-scale correlation analysis between urinary extracellular vesicle (uEV) and kidney