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PXD018363

PXD018363 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome-scale correlation analysis between urinary extracellular vesicle (uEV) and kidney
DescriptionWe profiled the proteomes of uEV and kidney from twelve rats. Six of them were under a standard diet while the other six under a high potassium diet for 4 days. During the revision stage of this project, we further put five rats in metabolic cages for two days, fed with the high potassium diet for 2 days. We made proteome-scale correlation analyses of uEV and kidney using absolute label-free quantification algorithm iBAQ under these three conditions: control, high K 4day, and high K 2 day. We also did label-free quantification (LFQ) to investigate the protein abundance changes in uEV and kidney between control and high K 4day.
HostingRepositoryPRIDE
AnnounceDate2021-07-28
AnnouncementXMLSubmission_2021-07-27_22:14:45.111.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterQi Wu
SpeciesList scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationListcarbamoylated residue; phosphorylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion; Q Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-04-04 09:17:42ID requested
12021-07-27 09:07:09announced
22021-07-27 22:14:45announced2021-07-28: Updated project metadata.
Publication List
10.1681/ASN.2020071035;
Wu Q, Poulsen SB, Murali SK, Grimm PR, Su XT, Delpire E, Welling PA, Ellison DH, Fenton RA, Large-Scale Proteomic Assessment of Urinary Extracellular Vesicles Highlights Their Reliability in Reflecting Protein Changes in the Kidney. J Am Soc Nephrol, 32(9):2195-2209(2021) [pubmed]
Keyword List
submitter keyword: urinary extracellular vesicle (uEV), kidney, correlation,proteome
Contact List
Robert A. Fenton
contact affiliationDepartment of Biomedicine, Aarhus University, Denmark
contact emailrobert.a.fenton@biomed.au.dk
lab head
Qi Wu
contact affiliationDepartment of Biomedicine, Aarhus University
contact emailqi.wu@biomed.au.dk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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