PXD018363 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteome-scale correlation analysis between urinary extracellular vesicle (uEV) and kidney |
Description | We profiled the proteomes of uEV and kidney from twelve rats. Six of them were under a standard diet while the other six under a high potassium diet for 4 days. During the revision stage of this project, we further put five rats in metabolic cages for two days, fed with the high potassium diet for 2 days. We made proteome-scale correlation analyses of uEV and kidney using absolute label-free quantification algorithm iBAQ under these three conditions: control, high K 4day, and high K 2 day. We also did label-free quantification (LFQ) to investigate the protein abundance changes in uEV and kidney between control and high K 4day. |
HostingRepository | PRIDE |
AnnounceDate | 2021-07-28 |
AnnouncementXML | Submission_2021-07-27_22:14:45.111.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Qi Wu |
SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116; |
ModificationList | carbamoylated residue; phosphorylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion; Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-04-04 09:17:42 | ID requested | |
1 | 2021-07-27 09:07:09 | announced | |
⏵ 2 | 2021-07-27 22:14:45 | announced | 2021-07-28: Updated project metadata. |
Publication List
10.1681/ASN.2020071035; |
Wu Q, Poulsen SB, Murali SK, Grimm PR, Su XT, Delpire E, Welling PA, Ellison DH, Fenton RA, Large-Scale Proteomic Assessment of Urinary Extracellular Vesicles Highlights Their Reliability in Reflecting Protein Changes in the Kidney. J Am Soc Nephrol, 32(9):2195-2209(2021) [pubmed] |
Keyword List
submitter keyword: urinary extracellular vesicle (uEV), kidney, correlation,proteome |
Contact List
Robert A. Fenton |
contact affiliation | Department of Biomedicine, Aarhus University, Denmark |
contact email | robert.a.fenton@biomed.au.dk |
lab head | |
Qi Wu |
contact affiliation | Department of Biomedicine, Aarhus University |
contact email | qi.wu@biomed.au.dk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD018363
- Label: PRIDE project
- Name: Proteome-scale correlation analysis between urinary extracellular vesicle (uEV) and kidney