PXD018343 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteome and PTMs analyses of mammary CAFs |
Description | To understand the molecular mechanisms that underpin pro-tumourigenic functions of cancer-associated fibroblasts (CAFs) we compared the proteome, acetylome, phosphoproteome of human immortalised breast cancer CAFs with those of the normal mammary fibroblasts that they were generated from. Based on the results obtained, we have also analysed proteome changes when CAFs were treated with the P300/CBP inhibitor c646. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:35:48.014.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Sara Zanivan |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue; acetylated residue |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-04-03 00:15:14 | ID requested | |
1 | 2022-04-10 02:22:53 | announced | |
⏵ 2 | 2024-10-22 05:35:48 | announced | 2024-10-22: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Human, breast cancer, acetylome, epigenetics, phosphoproteome, cancer-associated fibroblasts, proteome |
Contact List
Sara Zanivan |
contact affiliation | CRUK Beatson Institute |
contact email | s.zanivan@beatson.gla.ac.uk |
lab head | |
Sara Zanivan |
contact affiliation | Tumour Microenvironment & Proteomics |
contact email | s.zanivan@beatson.gla.ac.uk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD018343
- Label: PRIDE project
- Name: Proteome and PTMs analyses of mammary CAFs