PXD018326

PXD018326 is an original dataset announced via ProteomeXchange.

Title	Mouse kidney glomeruli. Control vs. podocin(R231Q/A268V)
Description	Similar to human patients, mice with the compound heterozygous mutation podocin R231Q/A268V, develop a late onset FSGS. Here, we did a proteomics anaylsis of kidney glomeruli before the onset of disease (mice at 3 weeks of age). Analysis of the data reveals that there are no developmental changes in the proteome of compund heterozygous mice.
HostingRepository	PRIDE
AnnounceDate	2020-05-15
AnnouncementXML	Submission_2020-08-11_03:22:24.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Martin Hoehne
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-04-01 08:36:52	ID requested
1	2020-05-15 04:51:56	announced
⏵ 2	2020-08-11 03:22:25	announced	2020-08-11: Updated publication reference for PubMed record(s): 32694662.

Butt L, Unnersj, ö, -Jess D, H, ö, hne M, Edwards A, Binz-Lotter J, Reilly D, Hahnfeldt R, Ziegler V, Fremter K, Rinschen MM, Helmst, ä, dter M, Ebert LK, Castrop H, Hackl MJ, Walz G, Brinkkoetter PT, Liebau MC, Tory K, Hoyer PF, Beck BB, Brismar H, Blom H, Schermer B, Benzing T, A molecular mechanism explaining albuminuria in kidney disease. Nat Metab, 2(5):461-474(2020) [pubmed]

submitter keyword: Kidney, glomerulus, NPHS2, podocin

Thomas Benzing
contact affiliation	1) Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany 2) CECAD, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany
contact email	thomas.benzing@uk-koeln.de
lab head
Martin Hoehne
contact affiliation	1) Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany 2) CECAD, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany
contact email	martin.hoehne@uk-koeln.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/05/PXD018326

PRIDE project URI

• PRIDE
  1. PXD018326
     1. Label: PRIDE project
     2. Name: Mouse kidney glomeruli. Control vs. podocin(R231Q/A268V)