PXD018291
PXD018291 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | A decision tree searching strategy to boost the identification of cross-linked peptides |
Description | We describe an efficient decision tree searching strategy (DTSS) to boost the identification of cross-linked peptides. The DTSS approach allows the identification of a wealth of complementary information to facilitate the construction of more protein-protein interaction networks for human cell lysate, which was tested by the use of a recently reported cross-linking dataset (ACS Cent. Sci. 2019, 5, 1514−1522). A variant of the PhoX-linker, named pDSPE was synthesized and applied to cross-link E.coli cell lysate to demonstrate that the acquisition of doubly charged ions can significantly improve identifica-tion results. The method can be seamlessly integrated to other search engines to maximize the number of identified cross-links |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-08 |
AnnouncementXML | Submission_2024-10-08_11:15:32.731.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD018291 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Wenzhang Chen |
SpeciesList | scientific name: Escherichia coli; NCBI TaxID: 562; |
ModificationList | Biotin:Sigma-B1267; Carbamidomethyl |
Instrument | Orbitrap Fusion ETD |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2020-03-30 15:31:26 | ID requested | |
⏵ 1 | 2024-10-08 11:15:42 | announced |
Publication List
10.1021/acs.analchem.0c00452; |
Huang R, Gao X, Xu Z, Zhu W, Wei D, Jiang B, Chen H, Chen W, Decision Tree Searching Strategy to Boost the Identification of Cross-Linked Peptides. Anal Chem, 92(20):13702-13710(2020) [pubmed] |
10.6019/PXD018291; |
Keyword List
submitter keyword: XLINK-MS, data-analysis |
Contact List
wenzhang chen | |
---|---|
contact affiliation | SIAIS, ShanghaiTech University |
contact email | chenwzh1@shanghaitech.edu.cn |
lab head | |
Wenzhang Chen | |
contact affiliation | Shanghaitech University |
contact email | chenwzh1@shanghaitech.edu.cn |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/11/PXD018291 |
PRIDE project URI |
Repository Record List
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