PXD018246

PXD018246 is an original dataset announced via ProteomeXchange.

Title	Human Cardiac Fibroblast BioID2 Interactome for SKI and TAZ(WWTR1)
Description	We used adenoviral-mediated overexpression of MYC-BioID2, MYC-BioID2-SKI, MYC-BioID2-WWTR1 (TAZ) in human primary cardiac fibroblasts to elucidate the interaction between SKI and the Hippo signaling pathway. Original data is also available on the Global Proteome Machine (http://hs2.proteome.ca/tandem/thegpm_tandem.html). Datasets are identified as follows: GPM10000002938 and 2939 are untreated negative control cell lysates; GPM10000002941 and 2942 are "empty" MYC-BioID2 vector; GPM10000002943 and 2944 are MYC-BioID2-SKI; and GPM10000002944 and 2945 are MYC-BioID2-WWTR1(TAZ).
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-08_18:00:46.256.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Natalie Landry
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-03-29 23:26:41	ID requested
⏵ 1	2021-09-08 18:00:46	announced

Landry NM, Rattan SG, Filomeno KL, Meier TW, Meier SC, Foran SJ, Meier CF, Koleini N, Fandrich RR, Kardami E, Duhamel TA, Dixon IMC, SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation. Basic Res Cardiol, 116(1):25(2021) [pubmed]

submitter keyword: BioID2, Cardiac fibroblast, Heart, SKI, Hippo, TAZ

Ian M. C. Dixon
contact affiliation	University of Manitoba Department of Physiology & Pathophysiology St. Boniface Hospital Albrechtsen Research Centre Institute of Cardiovascular Sciences
contact email	idixon@sbrc.ca
lab head
Natalie Landry
contact affiliation	University of Manitoba St. Boniface Hospital Albrechtsen Research Centre Institute of Cardiovascular Sciences
contact email	nlandry@sbrc.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD018246

PRIDE project URI

• PRIDE
  1. PXD018246
     1. Label: PRIDE project
     2. Name: Human Cardiac Fibroblast BioID2 Interactome for SKI and TAZ(WWTR1)