PXD018069

PXD018069 is an original dataset announced via ProteomeXchange.

Title	Child murder in the Early Bronze Age: proteomic sex identification of a cold case from Schleinbach, Austria
Description	The identification of sex-specific peptides in human tooth enamel by nanoflow liquid chromatography-tandem mass spectrometry (nanoLC-MS/MS) represents a quantum leap for the study of childhood and social relations more generally. Determining sex-related differences in prehistoric child rearing and mortality has been hampered by the inability to determine the biological sex of juveniles. We conducted nanoLC-MS/MS to identify sex-specific peptides in the dental enamel of a child from a settlement pit of the Early Bronze Age settlement of Schleinbach, Austria (c. 1950–1850 BC). Four perimortal impression fractures on the skull of the 5–6-year-old child indicate an intentional killing, with a co-buried loom weight as possible murder weapon. Proteomic analysis, conducted for the first time on prehistoric teeth in Austria, determined the child’s sex as male. While we cannot conclusively decide whether the child became the victim of conflicts between village groups or was slain by members of his own community, we suggest that contextual evidence points to the latter. A possible trigger of violence were the follow-on effects of an uncontrolled middle ear infection revealed by the osteological analysis. The boy from Schleinbach highlights the potential for further investigation of gender-biased violence, infanticide and child murder based on the recently developed method of proteomic sex identification.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:22:32.147.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Christopher Gerner
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-03-17 01:42:18	ID requested
1	2021-06-01 04:15:20	announced
⏵ 2	2024-10-22 05:22:33	announced	2024-10-22: Updated project metadata.

10.1007/s12520-020-01199-8;

Rebay-Salisbury K, Janker L, Pany-Kucera D, Schuster D, Spannagl-Steiner M, Waltenberger L, Salisbury RB, Kanz F, Child murder in the Early Bronze Age: proteomic sex identification of a cold case from Schleinbach, Austria. Archaeol Anthropol Sci, 12(11):265(2020) [pubmed]

submitter keyword: impression fractures, infanticide, peptides, proteomic sex identification,Bronze Age, otitis

Christopher Gerner
contact affiliation	University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry
contact email	christopher.gerner@univie.ac.at
lab head
Christopher Gerner
contact affiliation	University of Vienna
contact email	christopher.gerner@univie.ac.at
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD018069
     1. Label: PRIDE project
     2. Name: Child murder in the Early Bronze Age: proteomic sex identification of a cold case from Schleinbach, Austria