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PXD018053

PXD018053 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMouse early diabetic nephropathy LC-MS/MS analysis
DescriptionThe present study aims to evaluate the alterations induced by type I diabetes and the associated hyperglycemia on the proteome of renal tissue using a transgenic experimental animal model. Diabetic and non-diabetic kidney samples were analyzed by liquid nano-chromatography mass spectrometry and protein abundance was evaluated bylabel free quantification.
HostingRepositoryPRIDE
AnnounceDate2020-09-24
AnnouncementXMLSubmission_2020-09-24_01:06:35.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD018053
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterFelicia Antohe
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListL-cysteine residue; residues isobaric at 113.084064 Da; L-histidine residue; Deamidated; residues isobaric at 128.058578 Da; Oxidation; L-tyrosine residue; L-lysine residue; L-proline residue; Carbamidomethyl; residues isobaric at 71.037114 Da
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-03-13 06:40:31ID requested
12020-09-24 01:06:36announced
Publication List
Uyy E, Suica VI, Boteanu RM, Safciuc F, Cerveanu-Hogas A, Ivan L, Stavaru C, Simionescu M, Antohe F, Diabetic nephropathy associates with deregulation of enzymes involved in kidney sulphur metabolism. J Cell Mol Med, 24(20):12131-12140(2020) [pubmed]
Keyword List
submitter keyword: Mouse, kidney, Diabetes, LC-MS/MS
Contact List
Felicia Antohe
contact affiliationProteomics Department, Institute of Cellular Biology and Pathology, Romania
contact emailfelicia.antohe@icbp.ro
lab head
Felicia Antohe
contact affiliationInstitute of Cellular Biology and Pathology "N. Simionescu"
contact emailfelicia.antohe@icbp.ro
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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