PXD017944

PXD017944 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic analysis of scleraxis mutant tendon
Description	Tendons play fundamental role in the musculoskeletal system and locomotion by transferring forces generated by muscles to the skeleton. Tendon injuries can occur due to sports related incidents, as a result of trauma to overuse or during disease or ageing and are among the leading causes of musculoskeletal disability. Scleraxis is a marker of the tendon lineage and appears to be induced at the earliest stage of specification of this lineage, however little is known how scleraxis is modulating tendon growth activity. This study aimed to investigate how scleraxis modulates tendon cells activity.
HostingRepository	PRIDE
AnnounceDate	2021-09-08
AnnouncementXML	Submission_2021-09-08_14:09:55.946.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD017944
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Yalda Ashraf Kharaz
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	Oxidation; Carbamidomethyl
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-03-09 06:00:34	ID requested
⏵ 1	2021-09-08 14:09:56	announced

Publication List

Gumucio JP, Schonk MM, Kharaz YA, Comerford E, Mendias CL, Scleraxis is required for the growth of adult tendons in response to mechanical loading. JCI Insight, 5(13):(2020) [pubmed]

Gumucio JP, Schonk MM, Kharaz YA, Comerford E, Mendias CL, Scleraxis is required for the growth of adult tendons in response to mechanical loading. JCI Insight, 5(13):(2020) [pubmed]

Keyword List

submitter keyword: Tendon, Scleraxis, LC-MS/MS

submitter keyword: Tendon, Scleraxis, LC-MS/MS

Contact List

Dr. Christopher Mendias
contact affiliation	Associate Professor, HSS Reseach Institute, Weill Cornell Medical College, New York
contact email	mendiasc@HSS.EDU
lab head
Yalda Ashraf Kharaz
contact affiliation	University of Liverpool
contact email	yalda@liverpool.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD017944
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD017944

PRIDE project URI

Repository Record List

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