PXD017938

PXD017938 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	TTBK1/TTBK2 Phosphoproteomics in mouse cortical neurons
Description	TTBK1 and TTBK2 unique substrate identifications in mouse cortical neurons through global phosphoproteomics studies. shRNA for both TTBK1 or TTBK2 was used to treat mouse cortical neurons, to knockdown each kinase.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_07:48:04.028.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Bekim Bajrami
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	amidated residue; phosphorylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-03-09 04:04:14	ID requested
⏵ 1	2025-05-06 07:48:04	announced

Publication List

10.1007/s10571-020-00875-6;
Bao C, Bajrami B, Marcotte DJ, Chodaparambil JV, Kerns HM, Henderson J, Wei R, Gao B, Dillon GM, Mechanisms of Regulation and Diverse Activities of Tau-Tubulin Kinase (TTBK) Isoforms. Cell Mol Neurobiol, 41(4):669-685(2021) [pubmed]

10.1007/s10571-020-00875-6;

Bao C, Bajrami B, Marcotte DJ, Chodaparambil JV, Kerns HM, Henderson J, Wei R, Gao B, Dillon GM, Mechanisms of Regulation and Diverse Activities of Tau-Tubulin Kinase (TTBK) Isoforms. Cell Mol Neurobiol, 41(4):669-685(2021) [pubmed]

Keyword List

submitter keyword: Phosphoproteomics, shRNA, neurons, TTBK2,TTBk1

submitter keyword: Phosphoproteomics, shRNA, neurons, TTBK2,TTBk1

Contact List

Bekim Bajrami
contact affiliation	Chemical Bilology and Proteomics, Biogen, Cambridge, MA
contact email	bekim.bajrami@biogen.com
lab head
Bekim Bajrami
contact affiliation	Biogen
contact email	bekim.bajrami@biogen.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD017938
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD017938

PRIDE project URI

Repository Record List

[ + ]