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PXD017797

PXD017797 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePeptidome analysis of cerebrospinal fluid in neonates with hypoxic-ischemic brain damage
DescriptionHypoxic-ischemic brain injury (HIBD) causes neonatal death and serious neurological disability; however, there are currently no promising therapies for it excepting cooling. Therefore, in this study, we used peptidome analysis to identify differentially expressed peptides in cerebrospinal fluid (CSF) of neonates with HIBD or controls, which may give a foundation for finding new promising drugs of neonatal HIBD. CSF samples were collected from neonates with HIBD (n=4) or controls (n=4). ITRAQ LC-MS/MS was used to identify differentially expressed peptides between two groups.
HostingRepositoryiProX
AnnounceDate2020-03-01
AnnouncementXMLSubmission_2023-08-27_20:56:55.008.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXuewen Hou
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-03-01 19:52:23ID requested
12023-08-27 20:56:55announced
Publication List
Hou X, Yuan Z, Wang X, Cheng R, Zhou X, Qiu J, Peptidome analysis of cerebrospinal fluid in neonates with hypoxic-ischemic brain damage. Mol Brain, 13(1):133(2020) [pubmed]
Keyword List
submitter keyword: peptidomics, cerebrospinal fluid, neonates, hypoxic- ischemic brain damage
Contact List
Jie Qiu
contact affiliationChildren’s Hospital of Nanjing Medical University
contact emailqiujie@njmu.edu.cn
lab head
Xuewen Hou
contact affiliationChildren’s Hospital of Nanjing Medical University
contact emailhouxuewen1123@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI