PXD017730

PXD017730 is an original dataset announced via ProteomeXchange.

Title	Comparison of post-mating responses in the female reproductive tract among Drosophila species
Description	Fertility depends on the coordination of complex interactions between male and female reproductive proteins inside the female reproductive tract (FRT). These interactions mediate a suite of changes in female behavior, morphology, and physiology after mating, yet little is known about how the molecular environment of the FRT may differ among species and coordinate species-specific female post-mating responses. We used semi-quantitative proteomics to compare the FRT protein composition between virgin and mated females in Drosophila melanogaster. These results are compared to those from quantitative TMT proteomic analyses of the mating-induced changes in D. simulans and D. mauritiana, and after conspecific and heterospecific inseminations. Our study highlights the value of using quantitative proteomics approaches to study the molecular composition of the FRT environment, and how its divergence may inform mechanistic studies of post-mating pre-zygotic reproductive isolation between species.
HostingRepository	PRIDE
AnnounceDate	2020-06-25
AnnouncementXML	Submission_2020-06-25_04:51:41.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Erin McCullough
SpeciesList	scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-02-26 02:31:13	ID requested
⏵ 1	2020-06-25 04:51:42	announced

Dataset with its publication pending

submitter keyword: Drosophila melanogaster, female reproductive tract, post-mating responses, LC-M

Steve Dorus
contact affiliation	Center for Reproductive Evolution, Biology Department, Syracuse University
contact email	sdorus@syr.edu
lab head
Erin McCullough
contact affiliation	Syracuse University
contact email	mccullough.e@gmail.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD017730
     1. Label: PRIDE project
     2. Name: Comparison of post-mating responses in the female reproductive tract among Drosophila species