PXD017704

PXD017704 is an original dataset announced via ProteomeXchange.

Title	Protein Kinase A interacting proteins
Description	Find interactors of Protein kinase A (PKA) holoenzyme in human SCLC (H446) cells using LAP-tagged PRKACA, PRKACB and PRKAR1A proteins as baits. Tandem affinity purified complexes were analyzed using Bruker timsTOF Pro LC-MS mass spectrometer.
HostingRepository	PRIDE
AnnounceDate	2020-06-17
AnnouncementXML	Submission_2020-06-16_23:18:01.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD017704
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Janos Demeter
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Phospho; Glu->pyro-Glu; Deamidated; phosphorylated residue; Oxidation; Acetyl; acetylated residue; monohydroxylated residue; Carbamidomethyl; iodoacetamide derivatized residue; deamidated residue; Gln->pyro-Glu
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2020-02-24 07:30:25	ID requested
⏵ 1	2020-06-16 23:18:02	announced

Coles GL, Cristea S, Webber JT, Levin RS, Moss SM, He A, Sangodkar J, Hwang YC, Arand J, Drainas AP, Mooney NA, Demeter J, Spradlin JN, Mauch B, Le V, Shue YT, Ko JH, Lee MC, Kong C, Nomura DK, Ohlmeyer M, Swaney DL, Krogan NJ, Jackson PK, Narla G, Gordan JD, Shokat KM, Sage J, Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells. Cancer Cell, 38(1):129-143.e7(2020) [pubmed]

submitter keyword: Human

Julian Sage
contact affiliation	Professor of Pediatrics and Genetics co-Director of the Cancer Biology PhD program Harriet and Mary Zelencik Scientist in Children's Cancer and Blood Diseases 265 Campus Drive, SIM1 Bldg - Rm G2078a - Stanford, CA 94305-5457, USA
contact email	julsage@stanford.edu
lab head
Janos Demeter
contact affiliation	Stanford University
contact email	jdemeter@stanford.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD017704

PRIDE project URI

• PRIDE
  1. PXD017704
     1. Label: PRIDE project
     2. Name: Protein Kinase A interacting proteins