⮝ Full datasets listing

PXD017345

PXD017345 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSugarPy facilitates the universal, discovery-driven analysis of intact glycopeptides
DescriptionProtein glycosylation is a complex post-translational modification with crucial cellular functions in all domains of life. Currently, large-scale glycoproteomics approaches rely on glycan database dependent algorithms and are thus unsuitable for discovery-driven analyses of glycoproteomes. Therefore, we devised SugarPy, a glycan database independent Python module, and validated it on the glycoproteome of human breast milk. We further demonstrated its applicability by analyzing glycoproteomes with uncommon glycans stemming from the green algae Chalmydomonas reinhardtii and the archaeon Haloferax volcanii. Finally, SugarPy facilitated the novel characterization of glycoproteins from Cyanidioschyzon merolae.
HostingRepositoryPRIDE
AnnounceDate2021-03-09
AnnouncementXMLSubmission_2021-03-09_11:05:13.891.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterStefan Schulze
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Cyanidioschyzon merolae; NCBI TaxID: 45157; scientific name: Chlamydomonas reinhardtii; NCBI TaxID: 3055; scientific name: Haloferax volcanii; NCBI TaxID: 2246;
ModificationListmonohydroxylated residue; complex glycosylation; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-01-31 01:45:44ID requested
12021-03-09 11:05:14announced
Publication List
Schulze S, Oltmanns A, Fufezan C, Kr, ä, genbring J, Mormann M, Pohlschr, ö, der M, Hippler M, SugarPy facilitates the universal, discovery-driven analysis of intact glycopeptides. Bioinformatics, 36(22-23):5330-5336(2021) [pubmed]
Keyword List
submitter keyword: SugarPy, computational proteomics, glycoproteomics, glycosylation, IS-CID, LC-MS/MS, human breast milk, microalgae, archaea
Contact List
Michael Hippler
contact affiliationInstitute of Plant Biology and Biotechnology, University of Münster, 48143 Münster, Germany
contact emailmhippler@uni-muenster.de
lab head
Stefan Schulze
contact affiliationUniversity of Pennsylvania
contact emailsschulze@sas.upenn.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD017345
PRIDE project URI
Repository Record List
[ + ]