PXD017332 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion |
Description | The centriole-to-centrosome conversion is a mechanism of the centrosome maturation process that depends on the formation of a proper centriole wall structure. Beside the centriole wall biogenesis factors TUBD1 and TUBE1, CEP44 is involved in this process. Lack of CEP44 generates defects in the centriole wall structure and thus, it interferes with the centrosome maturation. POC1B was found to be an interactor of CEP44 in the immunoprecipitation and LC-MS experiment. The interaction and the function of this hit was validated with further independent biological experiments. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:01:27.983.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | elmar schiebel |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-01-30 02:30:37 | ID requested | |
1 | 2020-03-24 01:17:40 | announced | |
⏵ 2 | 2024-10-22 05:01:31 | announced | 2024-10-22: Updated project metadata. |
Publication List
Atorino ES, Hata S, Funaya C, Neuner A, Schiebel E, CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion. Nat Commun, 11(1):903(2020) [pubmed] |
10.1038/s41467-020-14767-2; |
Keyword List
curator keyword: Biological |
submitter keyword: Human, centriol-to-centrosome conversion, POC1B, centrosome, CEP44 |
Contact List
Elmar Johannes Schiebel |
contact affiliation | Zentrum für Molekulare Biologie, Universität Heidelberg, DKFZ-ZMBH Allianz, Heidelberg 69120, Germany |
contact email | e.schiebel@zmbh.uni-heidelberg.de |
lab head | |
elmar schiebel |
contact affiliation | ZMBH Uni Heidelberg |
contact email | e.schiebel@zmbh.uni-heidelberg.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD017332
- Label: PRIDE project
- Name: CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion