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PXD017332

PXD017332 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion
DescriptionThe centriole-to-centrosome conversion is a mechanism of the centrosome maturation process that depends on the formation of a proper centriole wall structure. Beside the centriole wall biogenesis factors TUBD1 and TUBE1, CEP44 is involved in this process. Lack of CEP44 generates defects in the centriole wall structure and thus, it interferes with the centrosome maturation. POC1B was found to be an interactor of CEP44 in the immunoprecipitation and LC-MS experiment. The interaction and the function of this hit was validated with further independent biological experiments.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:01:27.983.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterelmar schiebel
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-01-30 02:30:37ID requested
12020-03-24 01:17:40announced
22024-10-22 05:01:31announced2024-10-22: Updated project metadata.
Publication List
Atorino ES, Hata S, Funaya C, Neuner A, Schiebel E, CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion. Nat Commun, 11(1):903(2020) [pubmed]
10.1038/s41467-020-14767-2;
Keyword List
curator keyword: Biological
submitter keyword: Human, centriol-to-centrosome conversion, POC1B, centrosome, CEP44
Contact List
Elmar Johannes Schiebel
contact affiliationZentrum für Molekulare Biologie, Universität Heidelberg, DKFZ-ZMBH Allianz, Heidelberg 69120, Germany
contact emaile.schiebel@zmbh.uni-heidelberg.de
lab head
elmar schiebel
contact affiliationZMBH Uni Heidelberg
contact emaile.schiebel@zmbh.uni-heidelberg.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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