PXD017332

PXD017332 is an original dataset announced via ProteomeXchange.

Title	CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion
Description	The centriole-to-centrosome conversion is a mechanism of the centrosome maturation process that depends on the formation of a proper centriole wall structure. Beside the centriole wall biogenesis factors TUBD1 and TUBE1, CEP44 is involved in this process. Lack of CEP44 generates defects in the centriole wall structure and thus, it interferes with the centrosome maturation. POC1B was found to be an interactor of CEP44 in the immunoprecipitation and LC-MS experiment. The interaction and the function of this hit was validated with further independent biological experiments.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:01:27.983.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	elmar schiebel
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-30 02:30:37	ID requested
1	2020-03-24 01:17:40	announced
⏵ 2	2024-10-22 05:01:31	announced	2024-10-22: Updated project metadata.

Atorino ES, Hata S, Funaya C, Neuner A, Schiebel E, CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion. Nat Commun, 11(1):903(2020) [pubmed]

10.1038/s41467-020-14767-2;

curator keyword: Biological

submitter keyword: Human, centriol-to-centrosome conversion, POC1B, centrosome, CEP44

Elmar Johannes Schiebel
contact affiliation	Zentrum für Molekulare Biologie, Universität Heidelberg, DKFZ-ZMBH Allianz, Heidelberg 69120, Germany
contact email	e.schiebel@zmbh.uni-heidelberg.de
lab head
elmar schiebel
contact affiliation	ZMBH Uni Heidelberg
contact email	e.schiebel@zmbh.uni-heidelberg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/03/PXD017332

PRIDE project URI

• PRIDE
  1. PXD017332
     1. Label: PRIDE project
     2. Name: CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion