PXD017314

PXD017314 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of left ventricles containing the obscurin R4344Q mutation linked to hypertrophic cardiomyopathy and myocardia containing obscurin lacking Immunoglobulin domains 58/59 (Ig58/59)
Description	Cardiac lysates prepared from left ventricles of 1-year-old female wild-type mice, mice carrying the obscurin R4344Q mutation, and mice carrying obscurin lacking the Ig58/59 domains (ΔIg58/59) were subjected to isobaric tandem-mass tagging, liquid chromatography, and mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:07:31.371.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Li-Yen Hu
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-29 03:48:41	ID requested
1	2020-06-18 04:45:27	announced
⏵ 2	2024-10-22 05:07:39	announced	2024-10-22: Updated project metadata.

10.3389/fphys.2020.00478;

Hu LR, Kontrogianni-Konstantopoulos A, Proteomic Analysis of Myocardia Containing the Obscurin R4344Q Mutation Linked to Hypertrophic Cardiomyopathy. Front Physiol, 11():478(2020) [pubmed]

submitter keyword: arrhythmia, R4344Q mutation,Obscurin, mus musculus, dilated cardiomyopathy, hypertrophic cardiomyopathy

Aikaterini Kontrogianni-Konstantopoulos
contact affiliation	Department of Biochemistry and Molecular Biology, University of Maryland Baltimore
contact email	akontrogianni@som.umaryland.edu
lab head
Li-Yen Hu
contact affiliation	University of Maryland Baltimore
contact email	rebeccahu27@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD017314

PRIDE project URI

• PRIDE
  1. PXD017314
     1. Label: PRIDE project
     2. Name: Proteomic analysis of left ventricles containing the obscurin R4344Q mutation linked to hypertrophic cardiomyopathy and myocardia containing obscurin lacking Immunoglobulin domains 58/59 (Ig58/59)