PXD017216

PXD017216 is an original dataset announced via ProteomeXchange.

Title	Protective impact on the apoptotic pathway by suppressing DMT1 during inflammatory stress
Description	We performed phosphoproteomics using our sequential enrichment strategy of mRNA, protein, and phosphopeptides, which enabled us to explore the concurrent molecular events in the same sample and at the same time in normal and DMT1 silencing insulin-producing β-cells stimulated by siRNAs.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:24:28.906.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Taewook Kang
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-20 08:32:54	ID requested
1	2021-08-10 05:05:53	announced
⏵ 2	2024-10-22 05:24:29	announced	2024-10-22: Updated project metadata.

10.3390/ijms22158013;

Kang T, Huang H, Mandrup-Poulsen T, Larsen MR, Mediated Pancreatic Beta-Cell Pro-Apoptotic Signaling Pathways through the Autophagic Machinery. Int J Mol Sci, 22(15):(2021) [pubmed]

submitter keyword: degradation pathway, ROS, oxidative stress,diabetes, signaling

Martin R. Larsen
contact affiliation	Department of Biochemistry and Molecular Biology, University of Southern Denmark, Denmark.
contact email	mrl@bmb.sdu.dk
lab head
Taewook Kang
contact affiliation	University of Southern Denmark
contact email	taewookk@bmb.sdu.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD017216

PRIDE project URI

• PRIDE
  1. PXD017216
     1. Label: PRIDE project
     2. Name: Protective impact on the apoptotic pathway by suppressing DMT1 during inflammatory stress