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PXD017206

PXD017206 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSWATH-MS proteome of Moraxella catarrhalis under iron restricted conditions
DescriptionMoraxella catarrhalis is a human-restricted bacterial pathogen that causes otitis media in children and exacerbations of chronic obstructive pulmonary disease in adults. Iron is a co-factor required for the function of proteins involved in respiration and DNA replication, and thus is essential to life for most bacterial species. As iron is sequestered by host tissues, all host-adapted pathogens encounter periods of iron starvation. Previous studies have defined the repertoire of genes required for growth of M. catarrhalis under iron restricted conditions, and described differential expression at the transcriptional level. However, global changes in protein expression in response to iron starvation have not been investigated. Here we provide a SWATH-MS dataset describing differential expression of the M. catarrhalis CCRI-195ME proteome under iron restricted versus iron replete conditions.
HostingRepositoryPRIDE
AnnounceDate2020-01-24
AnnouncementXMLSubmission_2020-04-30_03:37:46.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLuke Blakeway
SpeciesList scientific name: Moraxella catarrhalis; NCBI TaxID: 480;
ModificationListNo PTMs are included in the dataset
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-01-20 08:18:26ID requested
12020-01-24 00:45:10announced
22020-04-30 03:48:54announced2020-04-30: Updated publication reference for PubMed record(s): 32193234.
Publication List
Blakeway LV, Tan A, Peak IR, Atack JM, Seib KL, Proteome of a Moraxella catarrhalis Strain under Iron-Restricted Conditions. Microbiol Resour Announc, 9(12):(2020) [pubmed]
Keyword List
submitter keyword: Moraxella catarrhalis, SWATH-MS, Iron restriction
Contact List
Kate L. Seib
contact affiliationInstitute for Glycomics, Griffith University, Gold Coast, Queensland, 4215, Australia
contact emailk.seib@griffith.edu.au
lab head
Luke Blakeway
contact affiliationInstitute for Glycomics, Griffith University
contact emailv.blakeway@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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