PXD017195

PXD017195 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Placental Growth Factor Regulates the Pentose Phosphate Pathway and Antioxidant Defense Systems in Human Retinal Endothelial Cells
Description	The molecular mechanisms whereby placental growth factor (PlGF) mediates its effects in nonproliferative diabetic retinopathy (DR) are unknown. To better understand the role of PlGF in DR, we used tandem mass tags (TMT)-labeled quantitative proteomics to human retinal endothelial cells (HRECs), treated anti-PlGF antibody as a experimental, PBS as a control.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:00:51.739.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Madhu Saddala Saddala
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-20 02:57:01	ID requested
1	2020-03-17 02:55:06	announced
⏵ 2	2024-10-22 05:00:52	announced	2024-10-22: Updated project metadata.

Publication List

10.1016/j.jprot.2020.103682;
Saddala MS, Lennikov A, Huang H, Placental growth factor regulates the pentose phosphate pathway and antioxidant defense systems in human retinal endothelial cells. J Proteomics, 217():103682(2020) [pubmed]

10.1016/j.jprot.2020.103682;

Saddala MS, Lennikov A, Huang H, Placental growth factor regulates the pentose phosphate pathway and antioxidant defense systems in human retinal endothelial cells. J Proteomics, 217():103682(2020) [pubmed]

Keyword List

ProteomeXchange project tag: EyeOME (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: TMT, Prdx6, KEGG,PlGF, PPP

ProteomeXchange project tag: EyeOME (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: TMT, Prdx6, KEGG,PlGF, PPP

Contact List

Dr. Hu Huang
contact affiliation	University of Missouri School of Medicine Columbia, MO-65201, USA
contact email	huangh1@missouri.edu
lab head
Madhu Saddala Saddala
contact affiliation	Johns Hopkins University School of Medicine
contact email	madhubioinformatics@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/03/PXD017195
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/03/PXD017195

PRIDE project URI

Repository Record List

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