PXD017191

PXD017191 is an original dataset announced via ProteomeXchange.

Title	Ensuring meiotic DNA break formation in the mouse pseudoautosomal region: ANKRD31 protein interactions
Description	Sex chromosomes in males of most mammalian species share only a small homologous segment, the pseudoautosomal region (PAR), wherein double-strand break (DSB) formation must occur for correct meiotic segregation. We find that multiple DSB-promoting factors hyperaccumulate in the PAR, including the ankyrin-repeat domain-containing protein ANKRD31. We used immunoprecipitation and mass spectrometry from extracts of juvenile mouse testes to identify potential ANKRD31-interacting proteins.
HostingRepository	PRIDE
AnnounceDate	2020-06-19
AnnouncementXML	Submission_2020-06-18_22:51:34.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhuoning Li
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-20 02:56:21	ID requested
⏵ 1	2020-06-18 22:51:35	announced

Acquaviva L, Boekhout M, Karasu ME, Brick K, Pratto F, Li T, van Overbeek M, Kauppi L, Camerini-Otero RD, Jasin M, Keeney S, Ensuring meiotic DNA break formation in the mouse pseudoautosomal region. Nature, 582(7812):426-431(2020) [pubmed]

submitter keyword: mouse

Scott Keeney
contact affiliation	Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
contact email	s-keeney@ski.mskcc.org
lab head
Zhuoning Li
contact affiliation	MSKCC
contact email	liz2@mskcc.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD017191

PRIDE project URI

• PRIDE
  1. PXD017191
     1. Label: PRIDE project
     2. Name: Ensuring meiotic DNA break formation in the mouse pseudoautosomal region: ANKRD31 protein interactions