PXD017128

PXD017128 is an original dataset announced via ProteomeXchange.

Title	Synaptamide activates the adhesion GPCR GPR110 through conformational changes induced by GAIN domain binding
Description	Ligand-induced conformational changes of GPR110 in cells probed by chemical cross-linking and mass specrtometry
HostingRepository	PRIDE
AnnounceDate	2020-05-27
AnnouncementXML	Submission_2020-05-26_17:05:33.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Bill Huang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-15 08:05:22	ID requested
⏵ 1	2020-05-26 17:05:34	announced

Huang BX, Hu X, Kwon HS, Fu C, Lee JW, Southall N, Marugan J, Kim HY, Synaptamide activates the adhesion GPCR GPR110 (ADGRF1) through GAIN domain binding. Commun Biol, 3(1):109(2020) [pubmed]

submitter keyword: GPR110, in-cell cross-linking, conformational changes, GAIN domain, LC-MS/MS

Hee-Yong Kim
contact affiliation	Laboratory of Molecular Signaling, National Institute on Alcohol Abuse and Alcoholism, NIH
contact email	hykim@nih.gov
lab head
Bill Huang
contact affiliation	NIH
contact email	bhuang@mail.nih.gov
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/05/PXD017128

PRIDE project URI

• PRIDE
  1. PXD017128
     1. Label: PRIDE project
     2. Name: Synaptamide activates the adhesion GPCR GPR110 through conformational changes induced by GAIN domain binding