PXD017040

PXD017040 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Cullin 3 Mouse Brain TMT-based Proteomics Analysis
Description	This project consists in 3 datasets: - Samples from adult mouse brains (Hippocampus, Cortex and Cerebellum): Cul3 +/- or +/+; 5 animals per condition. - Samples from embryonic mouse cortex: either Cul3 +/- or +/+ - Samples from embryonic mouse cortex: Cul3 fl/fl Emx-1-Cre ("hom"); Cul3 +/fl Emx1-Cre ("het") or Cul3+/fl ("control")
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:20:28.406.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Armel Nicolas
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; phosphorylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-09 09:15:19	ID requested
1	2021-03-25 23:14:38	announced
2	2021-05-28 06:14:14	announced	2021-05-28: Updated publication reference for PubMed record(s): 34031387.
⏵ 3	2024-10-22 05:20:29	announced	2024-10-22: Updated project metadata.

Publication List

10.1038/s41467-021-23123-x;
Morandell J, Schwarz LA, Basilico B, Tasciyan S, Dimchev G, Nicolas A, Sommer C, Kreuzinger C, Dotter CP, Knaus LS, Dobler Z, Cacci E, Schur FKM, Danzl JG, Novarino G, Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nat Commun, 12(1):3058(2021) [pubmed]

10.1038/s41467-021-23123-x;

Morandell J, Schwarz LA, Basilico B, Tasciyan S, Dimchev G, Nicolas A, Sommer C, Kreuzinger C, Dotter CP, Knaus LS, Dobler Z, Cacci E, Schur FKM, Danzl JG, Novarino G, Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nat Commun, 12(1):3058(2021) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: Mouse Brain Cullin 3 Cul3 Autism Cortex Cerebellum Hippocampus Embryonic Adult TMT DDA high pH RP

curator keyword: Biomedical

submitter keyword: Mouse Brain Cullin 3 Cul3 Autism Cortex Cerebellum Hippocampus Embryonic Adult TMT DDA high pH RP

Contact List

Gaia Novarino
contact affiliation	Genetic and Molecular Basis of Neurodevelopmental Disorders, IST Austria, Klosterneuburg, Lower Austria, Austria
contact email	gaia.novarino@ist.ac.at
lab head
Armel Nicolas
contact affiliation	IST Austria
contact email	armel.nicolas@ist.ac.at
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD017040
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD017040

PRIDE project URI

Repository Record List

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