PXD017002

PXD017002 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	HO-1/BMMSCs exosomes treating inflammatory injured IEC-6 cells LC-MSMS
Description	In this study, we established a rat small intestinal cell (IEC-6) injury model with tumor necrosis factor-α (TNF-α). Then, we added the exosomes from TNF- α damaged IEC-6 (TNF-α-exo), co-cultured with BMMSCs exosomes (BM-exo) and heme oxygenase-1 modified BMMSCs (HBM-exo) system exosomes into IEC-6 cells injured by TNF- α inflammation. After 48 hours, IEC-6 cells were collected for proteomic detection.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:07:52.785.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sun Dong
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-08 00:40:50	ID requested
1	2020-06-28 23:16:43	announced
⏵ 2	2024-10-22 05:07:53	announced	2024-10-22: Updated project metadata.

Publication List

Sun D, Cao H, Yang L, Lin L, Hou B, Zheng W, Shen Z, Song H, MiR-200b in heme oxygenase-1-modified bone marrow mesenchymal stem cell-derived exosomes alleviates inflammatory injury of intestinal epithelial cells by targeting high mobility group box 3. Cell Death Dis, 11(6):480(2020) [pubmed]
10.1038/s41419-020-2685-8;

Sun D, Cao H, Yang L, Lin L, Hou B, Zheng W, Shen Z, Song H, MiR-200b in heme oxygenase-1-modified bone marrow mesenchymal stem cell-derived exosomes alleviates inflammatory injury of intestinal epithelial cells by targeting high mobility group box 3. Cell Death Dis, 11(6):480(2020) [pubmed]

10.1038/s41419-020-2685-8;

Keyword List

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project, Stems Cells (B/D-HPP)
curator keyword: Biomedical
submitter keyword: rat；IEC-6s
HO-1；BMMSCs；LC-MSMS

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project, Stems Cells (B/D-HPP)

curator keyword: Biomedical

submitter keyword: rat；IEC-6s

HO-1；BMMSCs；LC-MSMS

Contact List

Dong Sun
contact affiliation	Tianjin First Central Hospital Clinic Institute, Tianjin Medical University, Tianjin, 300070, P.R. China
contact email	sansroy@163.com
lab head
Sun Dong
contact affiliation	Tianjin Medical University
contact email	sansroy@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD017002
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD017002

PRIDE project URI

Repository Record List

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