PXD016860

PXD016860 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Phosphoproteomic profiling of Acute Myeloid Leukaemia
Description	Acute Myeloid Leukaemia (AML) carries a 5 year survival rate of just 24%. Toxic chemotherapy regimens remain the backbone of standard of care for AML. The FLT3 tyrosine kinase is a recognised AML oncogene, with FLT3 activating mutations occurring in approximately one third of all AML patients. However, therapeutic targeting of FLT3 has proven difficult as monotherapy, with the development of drug resistance and relapse. Characterisation of the signalling pathways regulated by mutant FLT3 is required to identify better therapeutic strategies.
HostingRepository	MassIVE
AnnounceDate	2023-02-07
AnnouncementXML	Submission_2023-02-07_16:13:40.604.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Nikki Verrills
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Phospho; Oxidation; Deamidated; Acetyl; Carbamidomethyl; iTRAQ8plex
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2019-12-20 01:35:27	ID requested
⏵ 1	2023-02-07 16:13:41	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Phosphoproteomics, AML, FLT3

submitter keyword: Phosphoproteomics, AML, FLT3

Contact List

Nikki Verrills
contact affiliation	The University of Newcastle
contact email	Nikki.Verrills@newcastle.edu.au
lab head
Dr. Matt Dun
contact affiliation	University of Newcastle
contact email	Matt.Dun@newcastle.edu.au
lab head
Nikki Verrills
contact affiliation	The University of Newcastle, Australia
contact email	Nikki.Verrills@newcastle.edu.au
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000084730/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000084730/