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PXD016842

PXD016842 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleData in support of Mass spectrometric analysis of the in vitro secretome from equine bone marrow-derived mesenchymal stromal cells
DescriptionOsteoarthritis (OA) including joint inflammation and cartilage degradation is one of the leading causes of lameness in horses, but there is still no cure to prevent the progressive degradation of the joint tissue or restore normal joint anatomy. Therefore, the goals for the treatments used for decades has been to slow the progression of the disease, minimize pain, and increase the function of the joint. The aim of this study was to investigate differences in the in vitro secreted protein profile between naïve and chondrogenic differentiating BM-derived MSCs when exposed to an inflammatory (IL-1) environment.
HostingRepositoryPRIDE
AnnounceDate2020-05-25
AnnouncementXMLSubmission_2020-05-24_22:22:33.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAllan Stensballe
SpeciesList scientific name: Equus caballus (Horse); NCBI TaxID: 9796;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-12-19 05:55:01ID requested
12020-05-24 22:22:34announced
Publication List
Bundgaard L, Stensballe A, Elb, æ, k KJ, Berg LC, treatment. Stem Cell Res Ther, 11(1):187(2020) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: Horse, OA, secretome
Contact List
Allan Stensballe
contact affiliationAalborg University; Translational biomarkers
contact emailas@hst.aau.dk
lab head
Allan Stensballe
contact affiliationAalborg University
contact emailas@hst.aau.dk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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