PXD016834

PXD016834 is an original dataset announced via ProteomeXchange.

Title	Impact of Polyethylene on Salivary Glands Proteome in Galleria melonella
Description	Polyethylene pollutions are considered inert in nature and adversely affect the entire ecosystem. Larvae of greater wax moths (Galleria mellonella) have the ability to masticate and potentially biodegrade polyethylene films at elevated rates. The wax moth has been thought to metabolize PE independently of gut flora, however, the role of the microbiome is poorly understood and degradation by the wax moth might be involved. To determine whether the salivary glands of the wax moth were potentially involved in the PE degradation, it was investigated how surface changes of polyethylene were affected by mastication and consumption. Formation of pitting and degradation intermediates, including carbonyl groups, indicated that salivary glands could assist in polyethylene metabolism. We investigated the biochemical effect of exposure to PE on the composition of the salivary gland proteome. The expression of salivary proteins was found to be affected by PE exposure. The proteins that were significantly affected by the exposure to PE revealed that the wax moth is undergoing general changes in energy levels, and that enzymatic pathways associated with fatty acid beta oxidation were induced during PE consumption.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:00:50.829.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Nadieh de Jonge
SpeciesList	scientific name: Galleria mellonella; NCBI TaxID: 7137;
ModificationList	iodoacetamide derivatized amino-terminal residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2019-12-19 05:37:41	ID requested
1	2020-03-19 04:51:42	announced
⏵ 2	2024-10-22 05:00:54	announced	2024-10-22: Updated project metadata.

Peydaei A, Bagheri H, Gurevich L, de Jonge N, Nielsen JL, Impact of polyethylene on salivary glands proteome in Galleria melonella. Comp Biochem Physiol Part D Genomics Proteomics, 34():100678(2020) [pubmed]

10.1016/j.cbd.2020.100678;

curator keyword: Biological

submitter keyword: Greater wax moth, polyethylene, biodegradation, salivary glands

Jeppe Lund Nielsen
contact affiliation	Aalborg University Department of Chemistry and Bioscience Section of Biotechnology Head of Functional Ecology group Professor
contact email	jln@bio.aau.dk
lab head
Nadieh de Jonge
contact affiliation	Aalborg University
contact email	ndj@bio.aau.dk
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD016834
     1. Label: PRIDE project
     2. Name: Impact of Polyethylene on Salivary Glands Proteome in Galleria melonella