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PXD016797

PXD016797 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEffect of Shikonin on Aspergillus terreus
DescriptionAspergillus terreus is an emerging fungal pathogen in immunocompromised patients. Due to intrinsic resistance of AmB against A. terreus and acquiring resistance to azoles, alternative antifungal strategy needs investigation. Thus, we explored the activity of phytochemicals such as Shikonin, gallic acid, coumaric acid and quercetin against A. terreus. Amongst these, shikonin showed significant inhibition at MIC50;2 µg/ml, considered for proteome profiling.
HostingRepositoryPRIDE
AnnounceDate2021-06-19
AnnouncementXMLSubmission_2021-06-18_21:34:47.872.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJata Shankar
SpeciesList scientific name: Aspergillus terreus; NCBI TaxID: 33178;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-12-17 02:04:22ID requested
12021-06-18 21:34:48announced
Publication List
Shishodia SK, Shankar J, Proteomic analysis revealed ROS-mediated growth inhibition of Aspergillus terreus by shikonin. J Proteomics, 224():103849(2020) [pubmed]
Keyword List
submitter keyword: Amphotericin B
Catalase
Shikonin
Gallic acid
Biofilm
Oxidative stress
Contact List
Dr. Jata Shankar
contact affiliationAssitant Professor, Jaypee University of Information and Technology
contact emailjata_s@yahoo.com
lab head
Jata Shankar
contact affiliationJaypee University of information and technology
contact emailjata_s@yahoo.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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Repository Record List
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