PXD016797 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Effect of Shikonin on Aspergillus terreus |
Description | Aspergillus terreus is an emerging fungal pathogen in immunocompromised patients. Due to intrinsic resistance of AmB against A. terreus and acquiring resistance to azoles, alternative antifungal strategy needs investigation. Thus, we explored the activity of phytochemicals such as Shikonin, gallic acid, coumaric acid and quercetin against A. terreus. Amongst these, shikonin showed significant inhibition at MIC50;2 µg/ml, considered for proteome profiling. |
HostingRepository | PRIDE |
AnnounceDate | 2021-06-19 |
AnnouncementXML | Submission_2021-06-18_21:34:47.872.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jata Shankar |
SpeciesList | scientific name: Aspergillus terreus; NCBI TaxID: 33178; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-12-17 02:04:22 | ID requested | |
⏵ 1 | 2021-06-18 21:34:48 | announced | |
Publication List
Shishodia SK, Shankar J, Proteomic analysis revealed ROS-mediated growth inhibition of Aspergillus terreus by shikonin. J Proteomics, 224():103849(2020) [pubmed] |
Keyword List
submitter keyword: Amphotericin B |
Catalase |
Shikonin |
Gallic acid |
Biofilm |
Oxidative stress |
Contact List
Dr. Jata Shankar |
contact affiliation | Assitant Professor, Jaypee University of Information and Technology |
contact email | jata_s@yahoo.com |
lab head | |
Jata Shankar |
contact affiliation | Jaypee University of information and technology |
contact email | jata_s@yahoo.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD016797
- Label: PRIDE project
- Name: Effect of Shikonin on Aspergillus terreus