PXD016782 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Digestion of a variety of synthetic peptides by proteasomes |
Description | Proteasomes are large multi-subunit enzymes that act as the main producers of antigenic peptides presented at the cell surface to CD8+ T cells. They can simply cut proteins or recombine their fragments thereby generating novel sequences, i.e. spliced peptides via a process called proteasome-catalysed peptide splicing (PCPS). In order to gain more insight into these processes, we here perform in vitro digestions of 55 synthetic polypeptide substrates by proteasome isoforms followed by LC-MS/MS measurements using different Mass Spectrometers. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:01:57.606.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Artem Mansurkhodzhaev |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; deamidated residue |
Instrument | LTQ Orbitrap XL; Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-12-16 23:50:34 | ID requested | |
1 | 2020-04-14 02:22:55 | announced | |
2 | 2020-06-30 04:41:51 | announced | 2020-06-30: Updated publication reference for PubMed record(s): 32415162. |
⏵ 3 | 2024-10-22 05:01:59 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1038/s41597-020-0487-6; |
Specht G, Roetschke HP, Mansurkhodzhaev A, Henklein P, Textoris-Taube K, Urlaub H, Mishto M, Liepe J, Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes. Sci Data, 7(1):146(2020) [pubmed] |
Keyword List
submitter keyword: Synthetic peptides, proteasome, digestion, LC-MS/MS |
Contact List
Juliane Liepe |
contact affiliation | Head of research group Quantitative and Systems Biology; Max Planck Institute for Biophysical Chemistry; Goettingen;Germany |
contact email | juliane.liepe@mpibpc.mpg.de |
lab head | |
Artem Mansurkhodzhaev |
contact affiliation | Max Planck Institute for Biophysical Chemistry |
contact email | artem.mansurkhodzhaev@mpibpc.mpg.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/04/PXD016782 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD016782
- Label: PRIDE project
- Name: Digestion of a variety of synthetic peptides by proteasomes