PXD016779

PXD016779 is an original dataset announced via ProteomeXchange.

Title	Lysine methylome features in EZH2 wild-type and mutant lymphoma cell line
Description	We used EZH2i-targeted hematological malignancies as an examples and focused on molecular characterization of EZH2 Y641 mutant hematological cell lines. We used the proteomic strategies and compared the protein expression level and lysine methylation level (including mono-, di-, and trimethylaiton) in EZH2 wild-type (EZH2 WT), EZH2 Y641N and Y641F (EZH2 MUT) cell lines.
HostingRepository	iProX
AnnounceDate	2019-12-17
AnnouncementXML	Submission_2020-09-03_21:39:48.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jun-yu Xu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	monomethylated residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2019-12-16 21:33:17	ID requested
1	2019-12-16 21:35:44	announced
⏵ 2	2020-09-03 21:39:49	announced	2020-09-04: Update publication information

Hao B, Sun M, Zhang M, Zhao X, Zhao L, Li B, Zhai L, Liu P, Hu H, Xu JY, Tan M, Global characterization of proteome and lysine methylome features in EZH2 wild-type and mutant lymphoma cell lines. J Proteomics, 213():103614(2020) [pubmed]

submitter keyword: Lysine methylation, EZH2, diffuse large B cell lymphoma

Minjia Tan
contact affiliation	Chinese Academy of Sciences Shanghai Institute of Materia Medica
contact email	mjtan@simm.ac.cn
lab head
Jun-yu Xu
contact affiliation	Chinese Academy of Sciences Shanghai Institute of Materia Medica
contact email	XJY89089@163.com
dataset submitter

iProX dataset URI