PXD016713-1
PXD016713 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Chromatin bound O-GlcNAc proteins related to stress response and transcriptional regulation. |
Description | O-GlcNAcylation performs a critical role in regulating stress response program and cellular homeostasis. However, systematic studies of O-GlcNAc regulated genotoxic stress-responsive transcriptional reprograming have been limited. The GalNAz metabolic labeled global chromatin-associated proteins were isolated from the cross-linked MCF-7 and MCF-7/ADR cells nucleus, and then modified by downstream click-chemistry. The de-crosslinked O-GlcNAz chromatin-bound proteins were enriched for label-free quantitative proteomics by LC-MS/MS. |
HostingRepository | iProX |
AnnounceDate | 2019-12-12 |
AnnouncementXML | Submission_2020-07-05_23:18:19.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | yubo liu |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2019-12-11 23:48:52 | ID requested | |
⏵ 1 | 2020-07-05 23:18:20 | announced | |
2 | 2023-03-01 19:26:03 | announced | 2023-03-02: Update publication information. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: O-GlcNAc,metabolic labeling,proteomics |
Contact List
yubo liu | |
---|---|
contact affiliation | Dalian University of Technology |
contact email | liuyubo@dlut.edu.cn |
lab head | |
yubo liu | |
contact affiliation | Dalian University of Technology |
contact email | liuyubo@dlut.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |