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PXD016713

PXD016713 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleChromatin bound O-GlcNAc proteins related to stress response and transcriptional regulation.
DescriptionO-GlcNAcylation performs a critical role in regulating stress response program and cellular homeostasis. However, systematic studies of O-GlcNAc regulated genotoxic stress-responsive transcriptional reprograming have been limited. The GalNAz metabolic labeled global chromatin-associated proteins were isolated from the cross-linked MCF-7 and MCF-7/ADR cells nucleus, and then modified by downstream click-chemistry. The de-crosslinked O-GlcNAz chromatin-bound proteins were enriched for label-free quantitative proteomics by LC-MS/MS.
HostingRepositoryiProX
AnnounceDate2019-12-12
AnnouncementXMLSubmission_2020-07-05_23:18:19.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitteryubo liu
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-12-11 23:48:52ID requested
12020-07-05 23:18:20announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: O-GlcNAc´╝îmetabolic labeling´╝îproteomics
Contact List
yubo liu
contact affiliationDalian University of Technology
contact emailliuyubo@dlut.edu.cn
lab head
yubo liu
contact affiliationDalian University of Technology
contact emailliuyubo@dlut.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI