PXD016664

PXD016664 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of bronchoalveolar lavage fluid during invasive pulmonary aspergillosis in mice and humans
Description	Comprehensive proteomic analysis of the protein expression landscape of bronchoalveolar lavage fluid during invasive pulmonary aspergillosis in murine and human samples. 38 murine BALF samples (10 Aspergillus fumigatus infected mice without immunosuppression and without invasive pulmonary aspergillosis (IPA), 19 immunosuppressed and infected mice with IPA and 9 immunosuppressed animals without infection) were analysed for their global protein expression. In addition, 54 human BALF specimen from patients with probable IPA (23 samples), proven IPA (4 cases) and 27 control samples from patients with unrelated pulmonary diseases were analysed for their global protein composition. Host responses and Aspergillus fumigatus-specific proteins detectable in BALF were studied.
HostingRepository	PRIDE
AnnounceDate	2020-10-14
AnnouncementXML	Submission_2020-10-13_23:54:36.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mario Müller
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2019-12-09 06:10:23	ID requested
⏵ 1	2020-10-13 23:54:36	announced

Dataset with its publication pending

curator keyword: Biomedical

submitter keyword: BAL fluid, proteomics, invasive aspergillosis, Aspergillus fumigatus, bronchoalveolar lavage

Hortense Slevogt
contact affiliation	Host Septomics, ZIK Septomics, University Hospital Jena, Jena,Germany
contact email	hortense.slevogt@med.uni-jena.de
lab head
Mario Müller
contact affiliation	Host Septomics - ZIK Septomics Jena University Hosptial Jena Germany
contact email	mario.mueller1@med.uni-jena.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/10/PXD016664

PRIDE project URI

• PRIDE
  1. PXD016664
     1. Label: PRIDE project
     2. Name: Proteomic analysis of bronchoalveolar lavage fluid during invasive pulmonary aspergillosis in mice and humans