PXD016629

PXD016629 is an original dataset announced via ProteomeXchange.

Title	Nebulette reinforces podocyte structural integrity by linking actin and vimentin filaments
Description	One of the key aspects of the specialized podocyte morphology is the segregation and organization of distinct cytoskeletal filaments into different subcellular components, for which the exact mechanisms remain poorly understood. By screening the time-dependent proteomic changes within the rat puromycin aminonucleoside-induced nephropathy model, we identify the actin-binding protein nebulette as a unique component of the podocyte cytoskeleton that correlates strongly with glomerular function.
HostingRepository	PRIDE
AnnounceDate	2022-02-22
AnnouncementXML	Submission_2022-02-21_16:29:15.603.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD016629
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Tong Liu
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2019-12-06 04:04:08	ID requested
⏵ 1	2022-02-21 16:29:16	announced

Ge X, Zhang T, Yu X, Muwonge AN, Anandakrishnan N, Wong NJ, Haydak JC, Reid JM, Fu J, Wong JS, Bhattacharya S, Cuttitta CM, Zhong F, Gordon RE, Salem F, Janssen W, Hone JC, Zhang A, Li H, He JC, Gusella GL, Campbell KN, Azeloglu EU, LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments. J Am Soc Nephrol, 31(10):2372-2391(2020) [pubmed]

submitter keyword: nebulette, F-actin, podocytes, nephropathy

Evren U. Azeloglu
contact affiliation	Department of Medicine, Nephrology and Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
contact email	evren.azeloglu@mssm.edu
lab head
Tong Liu
contact affiliation	Rutgers University
contact email	linto@njms.rutgers.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD016629

PRIDE project URI

• PRIDE
  1. PXD016629
     1. Label: PRIDE project
     2. Name: Nebulette reinforces podocyte structural integrity by linking actin and vimentin filaments