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PXD016608

PXD016608 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors
DescriptionData contains results of LC-MS/MS analysis of KRAS4B-Q61H tyrosine phosphorylation following in vitro kinase reaction with Src kinase. Protein was denatured, reduced and alkylated and digested with Trypsin/Lys-C.
HostingRepositoryMassIVE
AnnounceDate2021-08-20
AnnouncementXMLSubmission_2021-08-20_05:29:56.125.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterJonathan St-Germain
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListDeamidated; Acetyl; Oxidation; Carbamidomethyl; Phospho
Instrumentinstrument model
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-12-04 08:16:36ID requested
12021-08-20 05:29:56announced
Publication List
no publication
Keyword List
submitter keyword: KRAS, LC-MS, tyorsine, phosphorylation, in vitro, kinase assay
Contact List
Brian Raught
contact affiliationPrincess Margaret Cancer Centre
contact emailbrian.raught@gmail.com
lab head
Jonathan St-Germain
contact affiliationPrincess Margaret Cancer Centre
contact emailjonstgermain@gmail.com
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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