PXD016399 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Aubergine protein interactors in 0-2 hour-Drosophila embryos |
Description | To identify Aub function in mRNA regulation in the Drosophila embryo, we have performed mass spectrometry analysis of Aub interactors, following immunoprecipitation of GFP-Aub in 0-2 hour-embryos. Immunoprecipitation of GFP alone was used as negative control. Because Aub accumulates at high levels in the germ plasm, GFP-Aub immunoprecipitation was also performed in oskar mutant embryos that do not assemble the germ plasm. Proteins coprecipitating with GFP-Aub were similar in wild-type and oskar mutant embryos. Translation factors were enriched among proteins coprecipitating with Aub. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:02:47.848.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Oana Vigy |
SpeciesList | scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227; |
ModificationList | monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-11-22 01:23:02 | ID requested | |
1 | 2020-04-27 02:57:39 | announced | |
⏵ 2 | 2024-10-22 05:02:48 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1038/s41422-020-0294-9; |
Ramat A, Garcia-Silva MR, Jahan C, Na, ï, t-Sa, ï, di R, Dufourt J, Garret C, Chartier A, Cremaschi J, Patel V, Decourcelle M, Bastide A, Juge F, Simonelig M, The PIWI protein Aubergine recruits eIF3 to activate translation in the germ plasm. Cell Res, 30(5):421-435(2020) [pubmed] |
Keyword List
submitter keyword: Aub |
PIWI protein |
translation |
Drosophila |
embryos |
Contact List
Martine Simonelig |
contact affiliation | mRNA Regulation and Development, Institute of Human Genetics, CNRS-Univ Montpellier, Montpellier, France |
contact email | Martine.Simonelig@igh.cnrs.fr |
lab head | |
Oana Vigy |
contact affiliation | FPP CNRS |
contact email | oana.vigy@fpp.cnrs.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD016399
- Label: PRIDE project
- Name: Aubergine protein interactors in 0-2 hour-Drosophila embryos