PXD016169

PXD016169 is an original dataset announced via ProteomeXchange.

Title	Stability of hair proteomes and proteomic genotyping with age and time
Description	Hair, a skin appendage, is a frequently procured biological specimen from crime scenes and has been used in forensic investigations for over a century. Proteomic analysis and identification of genetically variant peptides (GVPs) in hair samples for identification purposes is a recent but an efficiently advancing tool for forensic and archeological uses. However, the hair samples exposed to environmental insults have been seen to undergo degradation to various degrees depending on the physicochemical factors the samples have been exposed to. Therefore, one would expect that evidentiary hair samples stored for longer periods of time will undergo alterations in their proteomes and hence can affect their use on long-term samples stored as case work. To determine the degree to which age of individual or age of sample can affect the hair shaft proteome or inferred GVP profile, protein profiles of hair samples were compared from individuals of different ages as well as samples collected from same individual at different time points and stored in dry environment at room temperature for 5 - 65 years.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:07:13.478.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Glendon Parker
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-11-06 02:06:04	ID requested
1	2020-06-10 05:37:50	announced
⏵ 2	2024-10-22 05:07:21	announced	2024-10-22: Updated project metadata.

Plott TJ, Karim N, Durbin-Johnson BP, Swift DP, Scott Youngquist R, Salemi M, Phinney BS, Rocke DM, Davis MG, Parker GJ, Rice RH, Age-Related Changes in Hair Shaft Protein Profiling and Genetically Variant Peptides. Forensic Sci Int Genet, 47():102309(2020) [pubmed]

10.1016/j.fsigen.2020.102309;

submitter keyword: hair, genetically variant peptides,Hair protein profiles, forensic proteomics, proteomic genotyping

Glendon John Parker
contact affiliation	Environmental Toxicology, University of California Davis
contact email	gjparker@ucdavis.edu
lab head
Glendon Parker
contact affiliation	UC Davis
contact email	gjparker@ucdavis.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD016169

PRIDE project URI

• PRIDE
  1. PXD016169
     1. Label: PRIDE project
     2. Name: Stability of hair proteomes and proteomic genotyping with age and time