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PXD016127

PXD016127 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative Proteomic Profiling for Predicting Grade of Dysplasia in Intraductal Papillary Mucinous Neoplasm using Pancreatic Cyst Fluid
DescriptionThe increased number of pancreatic cyst lesions (PCLs) have been detected through the development of abdominal imaging techniques, such as computed tomography (CT), magnetic resonance imaging (MRI), and endoscopic ultrasound (EUS). However, accurate classification of cystic lesions is difficult because of the lack of standardized diagnostic methods, and thus potentially unnecessary surgical resection has been performed on pancreatic cyst patients. Among four most common types of cystic lesions of pancreas, intraductal papillary mucinous neoplasms (IPMNs), mucinous cystic neoplasms (MCN), serous cystic neoplasms (SCN), and solid pseudopapillary neoplasms (SPNs), IPMNs, the precursor lesion of pancreatic cancer, have been detected most frequently, and are subdivided into low-grade dysplasia (LGD), high-grade dysplasia (HGD), and invasive IPMN in accordance with their malignancy. To discover the potential biomarkers of the histological grades of IPMN, we investigated pancreatic cyst fluid proteins that are differentially expressed in accordance with the IPMN malignancy by LC-MS/MS analysis.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:12:14.967.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMisol Do
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-11-04 03:38:26ID requested
12020-09-09 03:27:56announced
22024-10-22 05:12:15announced2024-10-22: Updated project metadata.
Publication List
10.3390/cancers12092383;
Keyword List
submitter keyword: mucinous cystic neoplasm (MCN),pancreatic cyst fluid, biomarkers, intraductal papillary mucinous neoplasm (IPMN), serous cystic neoplasm (SCN), LC-MS/MS
Contact List
Youngsoo Kim
contact affiliationJoint faculty of Department of Biomedical Sciences & Biomedical Engineering, Seoul National University College of Medicine, 103 Daehak0ro, Seoul, Korea
contact emailbiolab@snu.ac.kr
lab head
Misol Do
contact affiliationSeoul National University College of Medicine
contact emailjm97129@naver.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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