PXD016020 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival |
Description | USP7, as a deubiquitination enzyme, controls ubiquitination and stability of Maf family proteins. USP7 promotes Maf transcriptional activity. Moreover, USP7 is overexpressed in multiple myeloma cells and its expression level is negatively correlated to the survival of myeloma patients. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:57:12.042.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jiefei Tong |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-10-25 02:35:11 | ID requested | |
1 | 2019-12-16 00:59:36 | announced | |
⏵ 2 | 2024-10-22 04:57:14 | announced | 2024-10-22: Updated project metadata. |
Publication List
He Y, Wang S, Tong J, Jiang S, Yang Y, Zhang Z, Xu Y, Zeng Y, Cao B, Moran MF, Mao X, The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival. J Biol Chem, 295(7):2084-2096(2020) [pubmed] |
10.1074/jbc.ra119.010724; |
Keyword List
submitter keyword: USP7, myeloma, Deubiquitinase, Maf |
Contact List
Mike Moran |
contact affiliation | Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada |
contact email | m.moran@utoronto.ca |
lab head | |
Jiefei Tong |
contact affiliation | Hospital for Sickkids |
contact email | jiefei.tong@sickkids.ca |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/12/PXD016020 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD016020
- Label: PRIDE project
- Name: The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival