PXD016020

PXD016020 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival
Description	USP7, as a deubiquitination enzyme, controls ubiquitination and stability of Maf family proteins. USP7 promotes Maf transcriptional activity. Moreover, USP7 is overexpressed in multiple myeloma cells and its expression level is negatively correlated to the survival of myeloma patients.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:57:12.042.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jiefei Tong
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2019-10-25 02:35:11	ID requested
1	2019-12-16 00:59:36	announced
⏵ 2	2024-10-22 04:57:14	announced	2024-10-22: Updated project metadata.

Publication List

He Y, Wang S, Tong J, Jiang S, Yang Y, Zhang Z, Xu Y, Zeng Y, Cao B, Moran MF, Mao X, The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival. J Biol Chem, 295(7):2084-2096(2020) [pubmed]
10.1074/jbc.ra119.010724;

He Y, Wang S, Tong J, Jiang S, Yang Y, Zhang Z, Xu Y, Zeng Y, Cao B, Moran MF, Mao X, The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival. J Biol Chem, 295(7):2084-2096(2020) [pubmed]

10.1074/jbc.ra119.010724;

Keyword List

submitter keyword: USP7, myeloma, Deubiquitinase, Maf

submitter keyword: USP7, myeloma, Deubiquitinase, Maf

Contact List

Mike Moran
contact affiliation	Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
contact email	m.moran@utoronto.ca
lab head
Jiefei Tong
contact affiliation	Hospital for Sickkids
contact email	jiefei.tong@sickkids.ca
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/12/PXD016020
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/12/PXD016020

PRIDE project URI

Repository Record List

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