PXD015949

PXD015949 is an original dataset announced via ProteomeXchange.

Title	Quantitative characterization of the neuropeptide level changes in dorsal horn and dorsal root ganglia regions of the murine itch models
Description	In this study, we performed a label-free relative quantitation to identify the peptide candidates correlated with itch sensation in murine models. We tested two different itch models-the AEW model (known commonly as the dry skin model) and the MC903 model. Performed peptide extraction from the dorsal horn (DH) and dorsal root ganglia regions of these two models and compared their levels with that of control mice.
HostingRepository	PRIDE
AnnounceDate	2020-01-23
AnnouncementXML	Submission_2020-01-23_03:59:18.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD015949
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Krishna Anapindi
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	Phospho; Amidated; Glu->pyro-Glu; Oxidation; Acetyl; Dehydro; Gln->pyro-Glu
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2019-10-22 01:25:21	ID requested
⏵ 1	2020-01-23 03:59:19	announced

Tillmaand EG, Anapindi KDB, De La Toba EA, Guo CJ, Krebs J, Lenhart AE, Liu Q, Sweedler JV, Quantitative Characterization of the Neuropeptide Level Changes in Dorsal Horn and Dorsal Root Ganglia Regions of the Murine Itch Models. J Proteome Res, 19(3):1248-1257(2020) [pubmed]

submitter keyword: LC-MS, label-free quantitation, extracted Ion chromatogram

Jonathan Sweedler
contact affiliation	Department of Chemistry, University of Illinois at Urbana Champaign
contact email	jsweedle@illinois.edu
lab head
Krishna Anapindi
contact affiliation	University of Illinois at Urbana Champaign
contact email	krishna.anapindi@gmail.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD015949
     1. Label: PRIDE project
     2. Name: Quantitative characterization of the neuropeptide level changes in dorsal horn and dorsal root ganglia regions of the murine itch models