PXD015948

PXD015948 is an original dataset announced via ProteomeXchange.

Title	Global Landscape of Native Protein Complexes in Synechocystis sp. PCC 6803
Description	Synechocystis sp. PCC 6803 is a model organism for study photosynthesis, energy metabolism, and environmental stress. It was the first fully sequenced phototrophic organism, but still nearly half of its proteome without functional annotation. In this study, we obtained 291 protein complexes, including 24092 PPIs among 2062 proteins by using co-fractionation and LC/MS/MS. From the protein network, we can learn more detail about how photosynthesis related to metabolism, cell motility, DNA repair, cell division, and other physiological processes. Meanwhile, the PPIs showed how protein function vary from bacterial to higher plant due to the protein interaction changed. It also allows us to uncover functions of hypothetical protein, such as Sll0445, Sll0446, Sll0447 participate in photosynthesis and cell motility, and Sll1334 regulates the expression of fatty acid. It is the most extensive protein interaction data in Synechocystis so far, which might provide critical insights into the fundamental molecular mechanism in Cyanobacterium.
HostingRepository	iProX
AnnounceDate	2019-10-22
AnnouncementXML	Submission_2023-03-01_23:02:36.826.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Bing Wang
SpeciesList	scientific name: Synechocystis sp. PCC 6803; NCBI TaxID: 1148;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-10-22 00:51:54	ID requested
1	2019-12-30 19:41:49	announced
⏵ 2	2023-03-01 23:02:37	announced	2023-03-02: Update publication information.

Xu C, Wang B, Yang L, Zhongming Hu L, Yi L, Wang Y, Chen S, Emili A, Wan C, Global Landscape of Native Protein Complexes in Synechocystis sp. PCC 6803. Genomics Proteomics Bioinformatics, 20(4):715-727(2022) [pubmed]

submitter keyword: Synechocystis sp. PCC 6803, Protein Complexes, Protein-Protein Interaction, Photosynthesis, Cyanobacterium

Cuihong Wan
contact affiliation	Central China Normal University
contact email	ch_wan@mail.ccnu.edu.cn
lab head
Bing Wang
contact affiliation	Central China Normal University
contact email	635819601@qq.com
dataset submitter

iProX dataset URI