PXD015927

PXD015927 is an original dataset announced via ProteomeXchange.

Title	The landscape of phospho-tyrosine mediated protein interactions of human receptor tyrosine kinases
Description	Systematically profiling the interactome of 1,144 unique wild-type and mutant phosphotyrosine residues of receptor tyrosine kinases by affinity enrichment - mass spectrometry (AE-MS), followed by a subset of novel interactors validation by competition assay.
HostingRepository	PRIDE
AnnounceDate	2022-10-06
AnnouncementXML	Submission_2022-10-06_12:19:03.574.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Runsheng Zheng
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos; Q Exactive HF-X; LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2019-10-21 00:46:45	ID requested
⏵ 1	2022-10-06 12:19:04	announced

Dataset with its publication pending

submitter keyword: cell signaling, receptor tyrosine kinases, tyrosine phosphorylation, interactome, affinity enrichment-mass spectrometry, protein-protein interaction, phosphotyrosine interacting domain, SH2 domain, PTB domain, hot-spot mutation, mutation‐gain tyrosine

Bernhard Kuster
contact affiliation	Chair of Proteomics and Bioanalytics Technische Universitaet Muenchen Germany
contact email	kuster@tum.de
lab head
Runsheng Zheng
contact affiliation	Technical University of Munich
contact email	runsheng.zheng@tum.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD015927

PRIDE project URI

• PRIDE
  1. PXD015927
     1. Label: PRIDE project
     2. Name: The landscape of phospho-tyrosine mediated protein interactions of human receptor tyrosine kinases