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PXD015896

PXD015896 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHeart ventricles proteomic profile in pulmonary arterial hypertension
DescriptionArterial pulmonary hypertension is a rare disease, with little knowledge regarding its etiology, and high mortality. Development of right and later on also left ventricular heart insufficiency, secondary to pulmonary hypertension, is a negative predictive factor. Genetic and molecular processes underlying left heart ventricle remodeling over the course of pulmonary hypertension remain unknown. In particular, there is no knowledge regarding the mechanisms of left heart ventricle atrophy which was completely avoided by researchers until recently.The aim of this study was to assess changes in protein abundance in left and right heart ventricle free wall of rats in monocrotaline model of PAH.
HostingRepositoryPRIDE
AnnounceDate2020-09-07
AnnouncementXMLSubmission_2020-09-07_00:05:31.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMaciej Suski
SpeciesList scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationListiodoacetic acid derivatized residue
InstrumentVelos Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-10-18 05:42:21ID requested
12020-09-07 00:05:33announced
Publication List
Ho, ł, da MK, Stachowicz A, Suski M, Wojtysiak D, Sowi, ń, ska N, Arent Z, Palka N, Podolec P, Kope, ć G, Myocardial proteomic profile in pulmonary arterial hypertension. Sci Rep, 10(1):14351(2020) [pubmed]
Keyword List
submitter keyword: heart, pulmonary hypertension, ventricle, monicrotaline, iTRAQ
Contact List
Rafał Olszanecki
contact affiliationChair of Pharmacology Faculty of Medicine Jagiellonian University Medical College 16 Grzegorzecka Street 31-531 Krakow, Poland tel: +48 12 4211168 fax: +48 12 4217217
contact emailrafal.olszanecki@uj.edu.pl
lab head
Maciej Suski
contact affiliationChair of Pharmacology
contact emailmaciej.suski@uj.edu.pl
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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