PXD015839 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | In planta bacterial multi-omics illuminates regulatory principles underlying plant-pathogen interactions |
Description | Gene regulation of bacterial pathogens in the host is not comprehensively understood due to the difficulty in analyzing genome-wide mRNA and protein expression of bacteria during infection. Here, we jointly analyzed transcriptome and proteome of a foliar bacterial pathogen in plants. Bacterial transcriptome changes can explain to a large extent their proteome changes in resistant and susceptible plants. However, a part of bacterial type III secretion system was suppressed by plant immunity preferentially at the protein level. Also, gene co-expression analysis uncovered previously unknown gene regulatory modules underlying bacterial virulence. Collectively, integrated in planta bacterial omics provides molecular insights into multiple layers of bacterial gene regulation that contributes to virulence and roles of plant immunity in controlling it. |
HostingRepository | PRIDE |
AnnounceDate | 2020-04-30 |
AnnouncementXML | Submission_2020-07-22_05:59:58.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Sara Christina Stolze |
SpeciesList | scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-10-15 23:53:17 | ID requested | |
1 | 2020-04-29 22:37:18 | announced | |
⏵ 2 | 2020-07-22 05:59:59 | announced | 2020-07-22: Updated publication reference for PubMed record(s): 32541952. |
Publication List
Nobori T, Wang Y, Wu J, Stolze SC, Tsuda Y, Finkemeier I, Nakagami H, Tsuda K, Multidimensional gene regulatory landscape of a bacterial pathogen in plants. Nat Plants, 6(7):883-896(2020) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: plant immunity, bacterial virulence, multi-omics |
Contact List
Hirofumi Nakagami |
contact affiliation | Basic Immune System of Plants / Protein Mass Spectrometry Max Planck Institute for Plant Breeding Research Carl-von-Linne-Weg 10, 50829 Cologne, Germany |
contact email | nakagami@mpipz.mpg.de |
lab head | |
Sara Christina Stolze |
contact affiliation | Plant Proteomics and Mass Spectrometry Group Max Planck Institute for Plant Breeding Research Carl-von-Linné Weg 10 50829 Cologne |
contact email | stolze@mpipz.mpg.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD015839
- Label: PRIDE project
- Name: In planta bacterial multi-omics illuminates regulatory principles underlying plant-pathogen interactions