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PXD015606

PXD015606 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteoViz: A toolset for interactive analysis of phosphoproteomics data
DescriptionQuantitative proteomics generates large datasets with increasing depth and quantitative information. Even after data processing and statistical analysis, interpreting the results and relating their significance back to the system of study remains challenging. Often, this process is performed by scientists with expertise in their field, but limited experience in proteomic or phosphoproteomic analysis. We developed a set of tools for simple, interactive exploration of phosphoproteomics data that can be easily interpreted into biological knowledge. These tools are designed to expedite the processes of reviewing raw data from statistical output, identifying and verifying enriched sequence motifs, and viewing the data from the perspective of functional pathways. Here, we present the workflow and demonstrate its functionality by analyzing a phosphoproteomic data set from two lymphoma cell lines treated with kinase inhibitors.
HostingRepositoryPRIDE
AnnounceDate2020-05-07
AnnouncementXMLSubmission_2020-05-07_02:25:52.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD015606
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterStephanie Byrum
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-09-26 03:44:50ID requested
12020-05-07 02:33:16announced
Publication List
Storey AJ, Naceanceno KS, Lan RS, Washam CL, Orr LM, Mackintosh SG, Tackett AJ, Edmondson RD, Wang Z, Li HY, Frett B, Kendrick S, Byrum SD, ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data. Mol Omics, 16(4):316-326(2020) [pubmed]
Keyword List
submitter keyword: phosphoproteomics, TMT, Shiny
Contact List
Stephanie Diane Byrum
contact affiliationDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205 Arkansas Children's Research Institute, Little Rock, AR
contact emailsbyrum@uams.edu
lab head
Stephanie Byrum
contact affiliationUAMS
contact emailsbyrum@uams.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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