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PXD015536

PXD015536 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLC-MS of S. cerevisiae scale-down cultivations
DescriptionChemostat cultivation mode imposes selective pressure on cells, which may result slow adaptation in the physiological state over time. We applied a two-compartment scale-down chemostat system simulating glucose gradients to characterize the long-term (100’s of hours) response of S. cerevisiae to fluctuating glucose concentrations. A wild-type strain and a recombinant strain, expressing an insulin precursor, were cultured in the scale-down system, and analyzed at the physiological and proteomic level. Phenotypes of both strains were compared to those observed in a well-mixed single chemostat system.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:06:53.945.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD015536
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterNaia Wright
SpeciesList scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-09-23 01:21:32ID requested
12020-06-08 17:30:34announced
22024-10-22 05:06:54announced2024-10-22: Updated project metadata.
Publication List
10.6019/PXD015536;
Keyword List
submitter keyword: scale-down, glucose gradients, fermentation, proteome,S. cerevisiae
Contact List
Markus Herrgard
contact affiliationThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Building 220, Kemitorvet, 2800 Kgs. Lyngby, Denmark
contact emailherrgard@biosustain.dtu.dk
lab head
Naia Wright
contact affiliationDTU
contact emailnarisa@biosustain.dtu.dk
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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