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PXD015512

PXD015512 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDifferent osteogenic differentiation behavior of canine mesenchymal stem cells derived from bone marrow and dental pulp: the proteomics profile
DescriptionAlthough various sources of cMSCs show similar characteristics, they are different in osteogenic potential due to their original cellular sources. Thus, this study was designed to globally explore and analyze the in vitro differentiation potential and behavior of canine bone-marrow derived mesenchymal stem cells (cBM-MSCs) and canine dental pulp stem cells (cDPSCs) toward osteogenic lineage. Global study of an in vitro osteogenic differentiation potential of the isolated cells was performed using proteomic-based analysis through mass spectrometry with dimethyl labelling method at day 7 and 14 post-induction, comparing with undifferentiated cells. The obtained results could be used as a comprehensive data and principal knowledge of the osteogenic differentiation potential of cBM-MSCs and cDPSCs in vitro and the trend of MSC-based tissue engineering for osteogenic regenerative therapy, concentrating on cMSCs application.
HostingRepositoryPRIDE
AnnounceDate2021-09-08
AnnouncementXMLSubmission_2021-09-08_14:34:16.292.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPoorichaya Somparn
SpeciesList scientific name: Canis lupus familiaris; NCBI TaxID: 9615;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-09-19 07:41:33ID requested
12021-09-08 14:34:17announced
Publication List
Nantavisai S, Pisitkun T, Osathanon T, Pavasant P, Kalpravidh C, Dhitavat S, Makjaroen J, Sawangmake C, Systems biology analysis of osteogenic differentiation behavior by canine mesenchymal stem cells derived from bone marrow and dental pulp. Sci Rep, 10(1):20703(2020) [pubmed]
Keyword List
submitter keyword: canine bone-marrow derived mesenchymal stem cells (cBM-MSCs), canine dental pulp stem cells (cDPSCs), osteogenic differentiation, systems biology
Contact List
Chenphop Sawangmake
contact affiliationDepartment of Pharmacology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand
contact emailchenphop@gmail.com
lab head
Poorichaya Somparn
contact affiliationChulalongkorn university
contact emailpoorichaya.s@chula.ac.th
dataset submitter
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Dataset FTP location
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PRIDE project URI
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