PXD015465

PXD015465 is an original dataset announced via ProteomeXchange.

Title	Multiplexed quantitative proteomics of extracellular vesicles released by endMSCs (EV-endMSCs)
Description	The extracellular vesicles released by endMSCs (EV-endMSCs)were characterized by multiplexedquantitative proteomics approach. We hypothesized that inflammatory priming of adult stem cells may contribute to increase their therapeutic effectiveness, thus, extracellular vesicles derived from IFN-γ-primed endMSCs (IFNγ/EV-endMSCs) were compared to control counterparts (n=3 patients).
HostingRepository	PRIDE
AnnounceDate	2019-12-17
AnnouncementXML	Submission_2020-02-17_02:59:54.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Inmaculada Jorge
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-09-16 04:45:48	ID requested
1	2019-12-17 06:53:40	announced
⏵ 2	2020-02-17 02:59:56	announced	2020-02-17: Updated publication reference for PubMed record(s): 31921832.

Marinaro F, G, ó, mez-Serrano M, Jorge I, Silla-Castro JC, V, á, zquez J, S, á, nchez-Margallo FM, Bl, á, zquez R, L, ó, pez E, Á, lvarez V, Casado JG, Unraveling the Molecular Signature of Extracellular Vesicles From Endometrial-Derived Mesenchymal Stem Cells: Potential Modulatory Effects and Therapeutic Applications. Front Bioeng Biotechnol, 7():431(2019) [pubmed]

submitter keyword: extracellular vesicles, human mesenchymal stem cells, endometrial, proteomic, IFNγ-primed

Javier G Casado
contact affiliation	Stem Cell Therapy Unit, Jesus Uson Minimally Invasive Surgery Centre, Cáceres, Spain
contact email	jgarcia@ccmijesususon.com
lab head
Inmaculada Jorge
contact affiliation	Vascular Biology and Inflammation
contact email	ijorge@cnic.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/12/PXD015465

PRIDE project URI

• PRIDE
  1. PXD015465
     1. Label: PRIDE project
     2. Name: Multiplexed quantitative proteomics of extracellular vesicles released by endMSCs (EV-endMSCs)