PXD015449
PXD015449 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Label-free quantitative proteomic analysis of rat liver tissue |
| Description | In this study, the spleen deficiency syndrome rat model was built with reserpine injection method. At first, the intervention effect of SJZD on spleen deficiency syndrome was preliminary evaluation through pharmacodynamics study. By comparing the differences proteins of liver tissues by label-free proteomics techniques, the differentially expressed proteins of spleen deficiency syndrome and SJZD intervention spleen deficiency syndrome were screened. At last, differentially expressed proteins were analyzed with bioinformatics analysis method, the potential target proteins of spleen deficiency syndrome and SJZD intervention spleen deficiency syndrome were excavated. At the same time, the corresponding metabolic pathways and biological molecular interaction network was established. We hope to probe the mechanisms of SJZD intervention spleen deficiency syndrome from the aspect of proteomic to provide a scientific basis for the clinical diagnosis and treatment of spleen deficiency syndrome. |
| HostingRepository | iProX |
| AnnounceDate | 2019-09-14 |
| AnnouncementXML | Submission_2023-03-01_19:07:55.198.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Qinghua Yan |
| SpeciesList | scientific name: Rattus rattus; NCBI TaxID: 10117; |
| ModificationList | monohydroxylated residue |
| Instrument | LTQ Orbitrap Velos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2019-09-14 19:59:40 | ID requested | |
| 1 | 2019-09-14 20:01:29 | announced | |
| ⏵ 2 | 2023-03-01 19:07:56 | announced | 2023-03-02: Update publication information. |
Publication List
| Pang Y, Ma M, Wang D, Xia J, Wang X, Hou L, Wang Z, Li X, Embryonic Stem Cell-Derived Exosomes Attenuate Transverse Aortic Constriction Induced Heart Failure by Increasing Angiogenesis. Front Cardiovasc Med, 8():638771(2021) [pubmed] |
Keyword List
| submitter keyword: Label-free quantitative proteomic analysis of rat liver tissue |
Contact List
| Qinghua Yan | |
|---|---|
| contact affiliation | Xinxiang Medical University, Xinxiang, Henan, China |
| contact email | yanqinghua1980@163.com |
| lab head | |
| Qinghua Yan | |
| contact affiliation | Xinxiang Medical University, Xinxiang, Henan, China |
| contact email | yanqinghua1980@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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